CRISPR Medicine News, 4 October 2020 | Truncated Guide RNAs Protect Off-Target Sites From CRISPR-Cas9 Editing & Missing Links - CRISPR Medicine

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Truncated Guide RNAs Protect Off-Target Sites From CRISPR-Cas9 Editing

Is off-target editing a concern in your CRISPR workflow? Doug Fowler at University of Washington has solved the problem with dead RNAs: truncated gRNAs that form a nonfunctional complex with Cas9 and shield the off-target sites from editing. Read all about it in our latest interview.

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