Thank You for reading

We have posted exciting new stories!

• A rare genetic form of diabetes has just been CRISPR'ed. Researchers use CRISPR-Cas9 gene editing to correct a diabetes-causing mutation in stem cells derived from patients. The edited stem cells can reverse severe diabetes in mice.
• Do you know your Cas9 from your Cas3? Our new overview of Cas endonucleases is here to help. We highlight the Cas endonucleases that are currently in focus for therapeutic applications.
• And speaking of Cas read our piece - Breaking the PAM Barrier - on the exciting research from Ben Kleinstivers' lab at Harvard engineering novel Cas9 variants that can target the entire human genome.

2020 overview of CRISPR clinical trials...

• And there are updates to our comprehensive list of all the gene-editing clinical studies. Have a look - it's a growing list, and we will keep it updated.

More good reads

• Testing and speed are essential for stopping the COVID19 pandemic. The first CRISPR-based COVID19 detection technology was published by Charles Chui in Nature Biotechnology and is much faster than the standard method. Also here.
• Here is an overview of two teams developing CRISPR-based detection of COVID19.
• Old-school video-game PACMAN gets a whole new twist. In a Cell pre-proof scientist at Stanford have developed a CRISPR-Cas13 strategy for shredding COVID19 in human lung epithelial cells.

Thank You for now - more great reads are on the way.

And if you have questions or suggestions, you can directly reach us at editor@crisprmedicinenews.com. We love hearing from readers!

(c; Rasmus

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