CRISPR Medicine News, 25 June 2020 | CRISPR for sickle cell disease and β-thalassemia - CRISPR Medicine

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Exciting news on clinical trials

  • Towards a CRISPR-cure for Sickle Cell Disease and β-thalassemia. Vertex and CRISPR Therapeutics have announced »remarkable and unprecedented data« from landmark CRISPR-Cas9 gene-editing clinical trial. The new data show patients don't need blood-transfusions up to 15 months after the therapy began and are symptom-free. CRISPR continues to live up to the hype, but the competition is getting hot.

  • And while on the topic of CRISPR clinical trials, a new study has just been added to our comprehensive overview. It's a study using CRISPR genome-edited off-the-shelf (allogeneic) T cells to target CD70-antigen-bearing kidney cancer cells. The study is sponsored by CRISPR Therapeutics and marks a transition from hematologic to solid tumours.

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(c; Rasmus

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