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Can CRISPR cure obesity?

With a novel and promising type of CRISPR gene therapy, we may be getting closer to a CRISPR cure for obesity. Scientists at Joslin Diabetes Center Harvard Medical School use dCas9 fused to transcriptional activators to change the fate of adipocytes. They use CRISPR to activate one silent gene in 'bad' white fat cells that turns the cells turn into 'good' fat-burning brown-like adipocytes. Mice transplanted with these cells gained less weight and displayed up to 35% improvements in glucose tolerance and insulin sensitivity compared to controls. Read the full story here.

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We are happy to announce two new additions to CRISPR Medicine News (c;

Student AssistantNethe Pedersen freshly graduated from college and with a strong interesting in biotechnology and chemistry. Nethe is passionate about new insights and learning experiences and excels at social media, where she looks forward to bring You more news from the frontier of the fast-moving and exciting CRISPR gene editing field.

Student AssistantLasse Jørgensen has a Bachelor's degree in Biochemistry and Molecular Biology and is currently pursuing a Master's degree in Computational Biomedicine at the University of Southern Denmark. Lasse is passionate about the therapeutic applications of genome editing and has hands-on experience with applying genome editing tools for the development of CAR T cells. He will help to research for CRISPR Medicine News and the Clinical Trials overview.

You can see who we are and read more in the About section.

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