CRISPR Medicine

Sanofi

Main (gene editing) focus: Blood diseases

Company stage: Commercial

Diseases: Sickle cell disease, beta-thalassemia

Genome editing tool: Zinc finger nucleases (ZFNs)

Funding stage: Public (NASDAQ:SNY)

Location: Paris, France

Website: https://www.sanofi.com/

Pipeline: https://www.sanofi.com/en/science-and-innovation/research-and-development/rd-pipeline

Partners: Sangamo Therapeutics


Sanofi is a large pharmaceutical company that is primarily involved in the gene-editing space through its collaboration with Sangamo Therapeutics. Two programmes are being developed under the collaboration: SAR445136 and ST-400 for sikcle cell disease and beta thalassemia, respectively. Both programmes are currently being tested in Phase 1/2 clinical trials, with postive preliminary results to date.

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