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Main (gene editing) focus: Blood diseases
Company stage: Commercial
Diseases: Sickle cell disease, beta-thalassemia
Genome editing tool: Zinc finger nucleases (ZFNs)
Funding stage: Public (NASDAQ:SNY)
Location: Paris, France
Partners: Sangamo Therapeutics
Sanofi is a large pharmaceutical company that is primarily involved in the gene-editing space through its collaboration with Sangamo Therapeutics. Two programmes are being developed under the collaboration: SAR445136 and ST-400 for sikcle cell disease and beta thalassemia, respectively. Both programmes are currently being tested in Phase 1/2 clinical trials, with postive preliminary results to date.