Base editors

| CRISPR Medicine | This is an overview of articles on base editors

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Diphtheria Toxin Selection Enables Site-Specific,...

Mar. 22, 2021

Almost complete efficiency of gene knock-in is achieved with a new CRISPR-based system developed by researchers from AstraZeneca. The system also...

New App Can Reveal Unintentional Mutations of a...

Feb. 15, 2021

DECODR's algorithm can quickly — and cheaply — make sense of Sanger sequencing data at a very precise level.

Haridha Shivram is Postdoctoral Researcher in Jennifer Doudna’s lab at University of California,...

An Arms Race Can Make the CRISPR Toolkit Even...

Feb. 8, 2021

A constant battle between prokaryotes and phages has shaped how CRISPR is controlled and regulated. Haridha Shivram from Jennifer Doudna’s lab is...

In Vivo Base Editing Corrects Rare Retinal Disease...

Jan. 11, 2021

Leber congenital amaurosis is a group of rare inherited retinal diseases that lead to blindness over time. Treatment options are limited,...

CRISPR Base Editors Offer First One-Time Treatment...

Jan. 6, 2021

The CRISPR gene-editing therapy more than doubled the lifespan in a mouse model by tackling the root cause of Hutchinson-Gilford progeria. The new...

The Future of CRISPR, As Kevin Davies Sees It

Jan. 4, 2021

Kevin Davies, author and Executive Editor of The CRISPR Journal, says that CRISPR is as close as doctors may be able to get to the Holy Grail of...

The Role of Gene Editing Within CAR T-Cell Therapy...

Nov. 3, 2020

Professor Waseem Qasim, of University College London and Great Ormond Street Institute of Child Health, helps run early-phase clinical trials using...

Truncated guide RNAs Protect Off-Target Sites from...

Oct. 2, 2020

Off-target editing is a significant problem with CRISPR and something that scientists really want to protect genomes from. And protection is exactly...