Prime editors

| CRISPR Medicine | This is an overview of articles on prime editors

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Multimodal Editing Maps Genetic Variants in EGFR

Dec. 2, 2024

Researchers at ETH Zürich have introduced a combined base and prime editing approach to explore the mutational landscape of the epithelial growth...

DTMP-Prime Model Advances Prime Editing...

CMN Briefs

Oct. 29, 2024

Researchers in Iran and Germany have developed a deep-learning model, DTMP-Prime, to improve predictions for Prime Editing (PE) efficiency and pegRNA...

Prime Editing Corrects Cystic Fibrosis Mutation

CMN Briefs

Jul. 11, 2024

Researchers have refined prime editing (PE) to correct the cystic fibrosis (CF) related gene CFTR. Results demonstrated improved efficiency and...

Large DNA Integrations With Prime Editing and...

May. 6, 2024

The FDA Has Cleared the First Clinical Trial...

CMN Clinical

May. 1, 2024

Prime Medicine announced this week that the FDA has cleared its investigational new drug application for PM359 for the treatment of chronic...

Priming Therapy: Pre-clinical Applications of...

Mar. 27, 2024

Prime Editing: CRISPR’s Final Evolution

Mar. 5, 2024

Revolving the Gene-Editing Landscape with Circular...

CMN Interview

Feb. 19, 2024

A recent breakthrough in gene-editing technology introduces circular RNA-mediated prime editors (CPEs), harnessing the Cas12a system to offer an...

Prime editors

| CRISPR Medicine | This is an overview of articles on prime editors

Sign-up to weekly Newsletter here.

T-cell Acute Lymphoblastic Leukaemia, T-ALL, (NCT05397184)
Sponsors:
Great Ormond Street Hospital for Children NHS Foundation Trust

IND Enabling

Phase I

Phase II

Phase III