Off-target

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CRISPRroots Incorporates RNA-seq to Evaluate Gene...

Dec. 8, 2021

Two critical points in evaluating the effects of CRISPR gene-editing experiments are validation of intended on-target modifications and testing for...

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CRISPR Off-Targets-II

Dec. 8, 2021

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CRISPR On/Off: Modelling and Predicting...

Nov. 5, 2021

Read more about the webinar - CRISPR On/Off

Webinar

CRISPR Off-Targets

Jun. 23, 2021

Read more about the webinar - CRISPR Off-Targets

CRISPECTOR Accurately Detects Translocations and...

Jun. 21, 2021

For the first time, adverse translocation events can be detected in multiplex PCR experiments after CRISPR editing. A new software tool, CRISPECTOR,...

CRISPR-Cas9 Causes Unintended On-Target Mutations...

Jun. 7, 2021

Researchers at the Francis Crick Institute in the UK recently discovered that CRISPR-Cas9 genome editing in early human embryos led to large...

Jan Gorodkin (left) is at the University of Copenhagen, Denmark. Yonglon Luo (right) is at Aarhus...

New Tool Offers Better Prediction of gRNA...

May. 31, 2021

A new deep learning model, CRISPRon, offers scientists more accurate gRNA on-target efficiency predictions than other existing tools. Massive,...

Simplest Possible Modification Rescues Dystrophin...

May. 3, 2021

Editing a single nucleotide in the largest human gene is sufficient to restore dystrophin production and myocyte function in Duchenne muscular...