Off-target

Kevin Davies, author and Executive Editor of The CRISPR Journal, says that CRISPR is as close as doctors may be able to get to the Holy Grail of...

CRISPR is set to change the face of medicine, and is already contributing to a huge number of clinical trials for a broad range of diseases....

With the Nobel Prize in Chemistry being awarded to the founding mothers of CRISPR - Emmanuelle Charpentier and Jennifer Doudna - genome editing is...

Off-target editing is a significant problem with CRISPR and something that scientists really want to protect genomes from. And protection is exactly...

In this roundup, we look back on our interviews with scientists who are making strides in developing CRISPR-based cures for genetic diseases.

Using massively parallel kinetic profiling, scientists can now characterise the cleavage and binding specificity of Cas variants for 10,000 targets at...

CRISPR genome editing marches forward as a curative therapy for genetic disorders. Here lead scientist Ayal Hendel talks about how he is developing a...

Scientists use CRISPR to change the fate of adipocytes, so bad fat is turned into good fat. Effectively treating fat with fat, this might help...