Genetic Engineering using CRISPR/Cas (Summer Course, Aarhus Denmark)

Genetic Engineering using CRISPR/Cas



Period: August 9 - August 20 2021

Level: Bachelor


Genetic engineering is becoming a cornerstone method in molecular and cellular biology, biotechnology, biomedicine, and soon in the Hospital setting to treat genetic diseases and to genetically manipulate cells, e.g. immune cells, to endow them with better properties.

This summer course will introduce state-of-the-art CRISPR/Cas systems and cover key applications in genetic engineering ranging from core gene editing applications to other capabilities of the system such as transcriptional and epigenetic regulation. The use of CRISPR/Cas for probing basic gene function will be described as well as the current status and future perspectives in therapeutic gene editing.

The course will have a specific focus on enabling the students to independently design and perform CRISPR experiments, which will be supported by virtual laboratory exercises. These will cover aspects ranging from the initial design considerations to the final analysis of gene editing outcomes.

The course is specifically intended for students with a particular interest in biomedical research.


Learning objectives:

  • to be able to describe the key principles and uses of the CRISPR/Cas-technique
  • to be able to provide an overview of the current status and relevance of the CRISPR/Cas-technology within biomedical research
  • to be able to evaluate and choose parameters relevant for gene editing projects such as choice of CRISPR platform, cell type, delivery method and vector design/platform
  • to be able to evaluate, select and interpret results from various assays for quantification of on- and off-target gene editing
  • to be able to use the attained knowledge to independently design and use CRISPR/Cas gene editing in an individual project
  • being able to analyse original literature within the field and use the literature to pose relevant research hypotheses



Course organizer: Rasmus O. Bak



Read CMN interview with Rasmus O. Bak here.

Course Details

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