Folding DNA into compact structures allows for efficient integration of large genes, and this might lead to new therapies for genetic diseases with...

2021 was a very successful year for CRISPR in the medical field. Much of the success comes down to gene editing without double-strand breaks,...

In 2021, we've seen positive clinical data for the first ever in vivo CRISPR medicines, base editors are heading for the clinic, and CRISPR therapies...

Mammoth Biosciences was until recently most well known as a diagnostic company using CRISPR technology, but through a newly announced partnership with...

Contraction kinetics of isogenic myofibers before and after CRISPR correction are compared in a microdevice with a light pulse. The optogenetic model...

Editing a single nucleotide in the largest human gene is sufficient to restore dystrophin production and myocyte function in Duchenne muscular...

DNA repair by a hitherto overlooked mechanism - non-homologous blunt-end joining – might lead to a new therapeutic strategy for Duchenne muscular...

CRISPR-Cas is seen as the holy grail in medicine for rare and incurable genetic diseases. In this piece, we take a look at what CRISPR can do for...