Researchers have developed a novel strategy to treat spinal muscular atrophy (SMA) by combining gene supplementation with CRISPR genome editing. The...
Using CRISPR-Cas9 to knock out CD5, researchers have significantly improved the efficacy of adoptive T-cell therapies for both haematological and...
Researchers have refined prime editing (PE) to correct the cystic fibrosis (CF) related gene CFTR. Results demonstrated improved efficiency and...
In a recent study, scientists introduced a new method for precise, simultaneous multi-site genome editing using retron arrays. The so-called multitron...
Researchers in Canada and China report the characterisation of AcrIF25, an anti-CRISPR protein that inhibits the type I-F CRISPR-Cas system by...
Allogene Therapeutics has activated the first clinical sites in a pivotal Phase 2 trial of cema-cel as first line consolidation treatment for large...
Researchers have developed a selective CRISPR-Cas9 strategy to target somatic mutations in pancreatic cancer cells, which is showing promising results...
Researchers have developed a new method for precise target selection by using unusual type DEDD transposases. The method, seekRNA, is based on the...