Conventional CRISPR-CAS9 tools trigger immune responses in host animals, which can systematically distort screening results and mask genuine cancer...
Two new biotech ventures pursuing heritable genome editing in embryos have raised concern among scientists, reigniting unresolved debates about...
Researchers have used a novel CRISPR-Cas library to identify essential microRNAs in prostate cancer cells, revealing miR-483-3p as a key regulator of...
A genome-wide CRISPR-Cas9 screen to identify transcription factor SOX2 as a critical regulator of PROM1, the gene encoding CD133, in glioblastoma stem...
Researchers at MIT today present DIAL, a modular framework that generates multiple stable expression levels from a single promoter through...
German researchers have employed a sophisticated CRISPR interference screening strategy to systematically investigate how transcription factors...
Chinese researchers have corrected a maple syrup urine disease mutation in patient-derived liver organoids using adenine base editing. The corrected...
Swiss scientists have employed in situ sequencing to track CRISPR-CAS base and prime editing events directly within intact mouse and macaque tissues...
