CRISPR cytosine base editors have been refined through directed evolution of enzyme recognition loops to enable highly precise DNA editing with...
A comprehensive CRISPR-CAS whole-genome screen has revealed key proteins controlling anti-sense oligonucleotide (ASO) activity, with a particular...
A tamoxifen-inducible CRISPRa/i system has been developed to enable reversible and rapid control of gene expression in mammalian cells. The platform...
A high-throughput prime editing screen in human cells reveals that some synonymous mutations, long considered functionally neutral, can significantly...
Chinese researchers have developed a thermosensitive, polyamine-modified hydrogel that significantly improves the co-delivery of CRISPR/Cas9 gene...
SNIPR Biome has dosed the first patient in its Phase 1b trial of SNIPR001, a CRISPR-CAS-armed bacteriophage therapy that represents a new frontier in...
A new computational framework called CCLMoff uses deep learning and RNA language models to predict off-target effects in CRISPR-CAS9 genome editing...
Modalis Therapeutics has partnered with SOLVE FSHD to advance the development of an experimental epigenome-editing therapy for facioscapulohumeral...
