Jennifer Doudna and colleagues have engineered a thermostable Cas9 variant, iGeoCas9, which dramatically enhances genome editing efficiency in...
Researchers in South Korea have developed a cadmium selenide (CdSe) quantum dot (Qdot) system to deliver CRISPR-Cas9 for gene editing in microglia,...
Scientists in China report a new nucleic acid detection assay based on aggregation-induced emission luminogens, which shows potential for the clinical...
In a move to potentially treat blindness, researchers have used CRISPR-Cas9 technology to permanently disrupt VEGFA expression in the eyes of rhesus...
A new study using CRISPR-Cas9 has identified key gene knockouts that restore activation of neural stem cells (NSCs) in ageing mice. The results...
German scientists have presented a dual modification strategy that combines CRISPR-Cas9 and CAR technology to enhance the efficacy of natural killer...
A new method combines multiplexed CRISPR-based gene activation (CRISPRa) with single-cell RNA sequencing (sc-RNA-seq) to identify cis-regulatory...
A novel engineered TadA ortholog-derived cytosine base editor (aTdCBE) can overcome existing limitations in motif preferences and adenosine activity...