A genome-wide CRISPR-Cas9 loss-of-function screening platform developed for primary human natural killer cells has identified several intracellular...
A new study from Stanford University combines CRISPR activation with single-cell and spatial approaches to identify mechanisms that enhance T...
Some of the best links we picked up around the internet
Spatial Perturb-seq enables pooled in vivo CRISPR screening with single-cell, whole-transcriptome readouts preserved within intact tissue...
A UK and Korean study has developed a machine learning pipeline that integrates single-cell RNA sequencing with CRISPR screens and protein network...
Researchers Profluent Bio have developed Protein2PAM, a deep learning model that predicts and engineers the protospacer-adjacent motif (PAM)...
Genome-wide CRISPR screens in isogenic cell lines have identified synthetic lethal targets across 15 frequently altered cancer drivers, offering new...
Researchers have built a CRISPR-based screening system that directly reads RNA splicing outcomes, using it to uncover medically relevant regulators of...