A new study from Stanford University combines CRISPR activation with single-cell and spatial approaches to identify mechanisms that enhance T...
Some of the best links we picked up around the internet
A redesigned CRISPR guide RNA system can now switch on multiple human genes in a fixed order, mimicking the staged logic of cell differentiation. The...
A tamoxifen-inducible CRISPRa/i system has been developed to enable reversible and rapid control of gene expression in mammalian cells. The platform...
Researchers have identified ARL11 as a critical factor in resistance to PARP inhibitor therapy through a genome-wide CRISPR activation screen,...
Scientists have developed a method that allows for simultaneous activation, repression, and knockout of genes within a single cell. By leveraging...
A new method combines multiplexed CRISPR-based gene activation (CRISPRa) with single-cell RNA sequencing (sc-RNA-seq) to identify cis-regulatory...
Researchers have engineered a minimal type I-F2 CRISPR-Cas system capable of transcriptional activation and base editing in human cells. This...
