A tamoxifen-inducible CRISPRa/i system has been developed to enable reversible and rapid control of gene expression in mammalian cells. The platform...
Scientists have developed a method that allows for simultaneous activation, repression, and knockout of genes within a single cell. By leveraging...
An engineered Cas12a variant offers high-efficiency activation and repression of multiple genes in a single experiment, with applications in cellular...
In 2022, we celebrate a decade of CRISPR as a game-changing tool in research and medicine. The last 10 years have been phenomenal, and CRISPR cures...
Researchers found a highly efficient repressor for CRISPRi experiments, ZIM3, which can repress gene expression far better than popular alternatives....