Researchers in the US have demonstrated that a single local injection of lentiviral particles carrying Cas9 and a MYOC-targeting gRNA reverses disease...

Researchers report the treatment of a genetic liver disease in mice through transient prime editor expression.

Excision BioTherapeutics reported positive interim clinical data for its HIV therapeutic candidate EBT-101 at this year's European Society for Gene &...

There are currently four clinical-stage gene-editing candidates in clinical trials for sickle cell disease, which affects millions of people worldwide...

In this roundup, we provide a summary of the ongoing gene-editing trials for beta thalassemia. This update includes trials sponsored by Vertex...

This week’s update looks at a Phase 1/2 study for ALLO-501A, a TALEN-edited CAR T-cell therapy for large B-cell lymphoma.

In recent years, researchers have turned to gene editing to address the limitations of CAR T therapies. This roundup summarises the clinical-stage...

This week's update features Iovance Biotherapeutics' new cancer immunotherapy candidate IOV-4001 that was recently cleared for clinical trial...