| CRISPR Medicine | This is an overview of our interviews
Researchers have successfully used CRISPR-Cas9 to selectively disrupt a mutant PSEN1 allele that causes familial Alzheimer’s disease. In this...
Researchers have developed a CRISPR-Cas9-based method to target β-catenin in disc cells. Using a mouse model of disc injury, they show that...
A CRISPR-based therapy for the metabolic liver disease phenylketonuria (PKU) has moved one step forward. In vivo prime editing in neonate mice...
An engineered Cas12a variant offers high-efficiency activation and repression of multiple genes in a single experiment, with applications in cellular...
Resistance to chemotherapy is a major challenge in the treatment of non-small cell lung cancer. By profiling the spectrum of outcomes arising from...
Most pharmaceuticals don't reach the brain, leaving cognitive impairments due to diseases like mucopolysaccharidoses (MPS) hard to treat. Now, a...
Researchers at Ulsan National Institute of Science and Technology in South Korea have developed a CRISPR-Cas9-based method to eliminate tumour cells....
Folding DNA into compact structures allows for efficient integration of large genes, and this might lead to new therapies for genetic diseases with...
