CRISPR-Cas CLINICAL TRIALS

All | TALENS | ZFN

Antibacterial

Urinary Tract Infections, UTI, (NCT04191148)
Sponsors:

Locus Biosciences

IND Enabling

Phase I

Phase II

Phase III

Blood

Beta-Thalassemia, (NCT03655678)
Sponsors:

Vertex Pharmaceuticals Incorporated

IND Enabling

Phase I

Phase II

Phase III

Sickle Cell Disease, (NCT03745287)
Sponsors:

Vertex Pharmaceuticals Incorporated

IND Enabling

Phase I

Phase II

Phase III

Human Immunodeficiency Virus Infection, HIV, (NCT03164135)
Sponsors:

Affiliated Hospital to Academy of Military Medical Sciences

IND Enabling

Phase I

Phase II

Phase III

Cancer

T-cell Acute Lymphoblastic Leukemia, ALL, (NCT03690011)
Sponsors:

Baylor College of Medicine

IND Enabling

Phase I

Phase II

Phase III

Nasopharyngeal Carcinoma, (NCT03044743)
Sponsors:

Yang Yang, MD, PhD, MSCR, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

IND Enabling

Phase I

Phase II

Phase III

Solid Tumor Adult, (NCT03747965)
Sponsors:

Chinese PLA General Hospital

IND Enabling

Phase I

Phase II

Phase III

B- cell Acute Lymphoblastic Leukaemia, ALL, (2019-003462-40)
Sponsors:

Great Ormond Street Hospital for Children NHS Trust

IND Enabling

Phase I

Phase II

Phase III

Non-Hodgkin Lymphoma, NHL, (2018-003916-38)
Sponsors:

CRISPR Therapeutics AG

IND Enabling

Phase I

Phase II

Phase III

Multiple Solid Tumor Adult, (NCT03545815)
Sponsors:

Chinese PLA General Hospital

IND Enabling

Phase I

Phase II

Phase III

Multiple Myeloma, (NCT03399448)
Sponsors:

University of Pennsylvania

IND Enabling

Phase I

Phase II

Phase III

Multiple Myeloma, (NCT04244656)
Sponsors:

CRISPR Therapeutics AG

IND Enabling

Phase I

Phase II

Phase III

Metastatic Non-small Cell Lung Cancer, NSCLC, (NCT02793856)
Sponsors:

Sichuan University

IND Enabling

Phase I

Phase II

Phase III

Acute Lymphoblastic Leukemia, ALL, (NCT04037566)
Sponsors:

Xijing Hospital, The Fourth Military Medical University

IND Enabling

Phase I

Phase II

Phase III

Invasive Bladder Cancer, IBC, (NCT02863913)
Sponsors:

Peking University

IND Enabling

Phase I

Phase II

Phase III

Human papillomavirus (HPV) related cervical cancer, (NCT03057912)
Sponsors:

First Affiliated Hospital, Sun Yat-Sen University

IND Enabling

Phase I

Phase II

Phase III

Esophageal Cancer, (NCT03081715)
Sponsors:

Hangzhou Cancer Hospital

IND Enabling

Phase I

Phase II

Phase III

B-cell Malignancy, (NCT04035434)
Sponsors:

CRISPR Therapeutics AG

IND Enabling

Phase I

Phase II

Phase III

B Cell Lymphoma, (NCT03166878)
Sponsors:

Chinese PLA General Hospital

IND Enabling

Phase I

Phase II

Phase III

Eye

Leber Congenital Amaurosis, (NCT03872479)
Sponsors:

IND Enabling

Phase I

Phase II

Phase III

Metabolic disorder