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Lempo Therapeutics

Main focus: Gene editing-based treatments for attenuating chronic disease

Company stage: Pre-clinical

Diseases (gene editing): Pulmonary Arterial Hypertension, PAH

Genome editing tool: CRISPR-Cas9

Funding stage: Private

Location: Binyamina, Israel

Website: https://www.lempo-tx.com/

Pipeline: https://www.lempo-tx.com/

Lempo Therapeutics is an Israel-based, pre-clinical gene editing company, utilising CRISPR-Cas9 to edit stem-cells ex vivo, to inactivate disease causing myeloperoxidase (MPO) proteins in patients suffering from pulmonary arterial hypertension. Using CRISPR, Lempo edits CD34+ cells to knock out the MPO gene, after which the cells can be reinfused into patients.

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Company: Lempo Therapeutics
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