CRISPR Tsunami is a 1-day introductory course to computational Cas9-gRNA design. The course is designed for Master’s/PhD students and researchers who are interested in the CRISPR/Cas9 genome editing tool and would like to apply it in their experiments, but have little or no experience in designing efficient and specific gRNAs (the variable component in the system).

The course will begin with an introduction on the CRISPR/Cas9 tool and the importance of gRNA design. Methods and tools to design gRNAs for different applications (gene knockout, knockin, base editing…) will also be covered in the introduction. The recent techniques for the massive generation of CRISPR/Cas9 activity data and for the computational prediction of gRNA activity via machine learning and heuristic approaches will be the focus of the morning lectures.

In the afternoon, some of the tools presented will be employed during gRNA design exercises. Attendees are welcome to bring their own data/study case and design their own gRNAs.

The course, including the hands-on session, is free of charge.

You can sign up for morning lectures 9-12 only, or both morning lectures and afternoon hands-on session 9-16:30 (limited seats).

Date: September 10, 9:00-16:30, 2021

Place: Online

Deadline: August 20, 2021

Sign-up here.

N.B please note that everyone will be put on the waiting list for the course until the registration closes. Those who have received a spot on the course will then receive a confirmation email.

Organisers:

Jan Gorodkin (1, 2) and Giulia I Corsi (1)
(1) Center for non-coding RNA in Technology and Health, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences,University of Copenhagen
(2) Center for Health Data Science, Faculty of Health and Medical Sciences,University of Copenhagen