Swiss scientists have employed in situ sequencing to track CRISPR-CAS base and prime editing events directly within intact mouse and macaque tissues...

Researchers in Spain have used CRISPR-Cas9 to engineer human cord blood CD34⁺ HSPCs to model the haematologic, immunologic and vascular disorders...

Spanish researchers have developed a CRISPR-CAS High Fidelity system that specifically targets G12C and G12D mutations in non-small cell lung cancer....

Scientists have developed a novel gene editing system that significantly enhances targeted gene integration without using viral vectors. The 'enGager'...

CRISPR-StAR, a novel screening technique, addresses the challenges of genetic screening in complex in vivo models by using internally controlled...

Researchers have investigated the impact of genome-edited RUNX1 loci on bone formation, revealing the regulatory influence of non-coding GWAS variants...

A new method for directly editing T-cells in lymph nodes using CRISPR-Cas9 aims to enhance immune checkpoint blockade (ICB) cancer therapies. The...

CRISPR gene editing can lead to integration of mitochondrial DNA (mtDNA) fragments into the nuclear genome, raising potential safety concerns in...