CRISPR-StAR, a novel screening technique, addresses the challenges of genetic screening in complex in vivo models by using internally controlled...

Researchers have investigated the impact of genome-edited RUNX1 loci on bone formation, revealing the regulatory influence of non-coding GWAS variants...

A new method for directly editing T-cells in lymph nodes using CRISPR-Cas9 aims to enhance immune checkpoint blockade (ICB) cancer therapies. The...

CRISPR gene editing can lead to integration of mitochondrial DNA (mtDNA) fragments into the nuclear genome, raising potential safety concerns in...

Delivering mRNA via acid-degradable nanoparticles offers a new frontier in prenatal gene editing, setting the stage for treatments targeting the root...

In a move to potentially treat blindness, researchers have used CRISPR-Cas9 technology to permanently disrupt VEGFA expression in the eyes of rhesus...

Researchers in South Korea have introduced a novel microfluidic platform, termed Droplet Cell Pincher (DCP), to enhance CRISPR-Cas9 genome editing....

Researchers have developed a novel strategy to treat spinal muscular atrophy (SMA) by combining gene supplementation with CRISPR genome editing. The...