There are currently four clinical-stage gene-editing candidates in clinical trials for sickle cell disease, which affects millions of people worldwide...

In a recent study, researchers in the U.S. and Australia engineered bacteria that can detect specific extracellular DNA sequences and mutations from...

With no effective treatments available, brain metastases are associated with extremely low survival rates. In their latest work, Khalid Shah’s team at...

In this roundup, we provide a summary of the ongoing gene-editing trials for beta thalassemia. This update includes trials sponsored by Vertex...

Intellia Therapeutics recently shared new positive clinical data from the ongoing Phase 1 trial of NTLA-2002 in hereditary angioedema (HAE). NTLA-2002...

A one-shot CRISPR cure for HIV may be in sight with a new approach that eliminated replication-competent virus in 58% of infected mice. The method...

Intellia Therapeutics recently announced that the FDA has cleared an Investigational New Drug application for NTLA-2002, a single-dose in vivo CRISPR...

In recent years, researchers have turned to gene editing to address the limitations of CAR T therapies. This roundup summarises the clinical-stage...