Two new biotech ventures pursuing heritable genome editing in embryos have raised concern among scientists, reigniting unresolved debates about...
Researchers have used a novel CRISPR-Cas library to identify essential microRNAs in prostate cancer cells, revealing miR-483-3p as a key regulator of...
A genome-wide CRISPR-Cas9 screen to identify transcription factor SOX2 as a critical regulator of PROM1, the gene encoding CD133, in glioblastoma stem...
Researchers at MIT today present DIAL, a modular framework that generates multiple stable expression levels from a single promoter through...
German researchers have employed a sophisticated CRISPR interference screening strategy to systematically investigate how transcription factors...
Chinese researchers have corrected a maple syrup urine disease mutation in patient-derived liver organoids using adenine base editing. The corrected...
Swiss scientists have employed in situ sequencing to track CRISPR-CAS base and prime editing events directly within intact mouse and macaque tissues...
Researchers in Spain have used CRISPR-Cas9 to engineer human cord blood CD34⁺ HSPCs to model the haematologic, immunologic and vascular disorders...
