A study published today in Nature Communications demonstrates a CRISPR-Cas9 strategy for engineering haematopoietic stem and progenitor cells (HSPCs)...
Researchers have identified ARL11 as a critical factor in resistance to PARP inhibitor therapy through a genome-wide CRISPR activation screen,...
A Spanish study explores a CRISPR-based gene therapy approach for Ewing sarcoma. The in vivo treatment reduced tumour growth in mice, with no...
Researchers in the UK report a clinically-relevant transplantation strategy using CRISPR-corrected human myogenic cells in hydrogels that generate...
An American study has explored how enlarging the recognition (REC) domain of CRISPR-Cas9 can improve adenine base editing accuracy. The researchers at...
A new technique developed by Jennifer Doudna and colleagues at the University of California, Berkeley, achieves single-molecule resolution imaging of...
Focused ultrasound (FUS) can significantly improve the efficiency of CRISPR-based genome editing in the brain, according to a new study from the...
Researchers have used a two-guide CRISPR knock-in technique to replace the entire coding sequence (CDS) of the synaptic LRRTM2 protein (Leucine-Rich...
