German researchers have employed a sophisticated CRISPR interference screening strategy to systematically investigate how transcription factors...
Chinese researchers have corrected a maple syrup urine disease mutation in patient-derived liver organoids using adenine base editing. The corrected...
Swiss scientists have employed in situ sequencing to track CRISPR-CAS base and prime editing events directly within intact mouse and macaque tissues...
Researchers in Spain have used CRISPR-Cas9 to engineer human cord blood CD34⁺ HSPCs to model the haematologic, immunologic and vascular disorders...
A plasmid-delivered prime editing strategy corrected the glucose-6-phosphate dehydrogenase (G6PD) Viangchan (c.871G>A) mutation in engineered HEK293T...
CRISPR-Cas12b technology was used to edit allogeneic donor islet cells for transplantation into a man with long-standing type 1 diabetes....
Building on prior work demonstrating HIV-1 elimination using dual CRISPR-Cas9 editing and antiretroviral therapy in humanised mice, this study by...
CRISPR cytosine base editors have been refined through directed evolution of enzyme recognition loops to enable highly precise DNA editing with...
