A new CRISPR-based method has been developed to functionally validate hits from pooled knockout screens by measuring shifts in indel profiles that...
A new strategy enables precise spatial and temporal control of CRISPR gene editing using chemically modified, photo-responsive guide RNAs. This...
A new review outlines genetic engineering strategies, including CRISPR, to enhance the therapeutic potential of innate immune cells in cancer...
A study published today in Nature Communications demonstrates a CRISPR-Cas9 strategy for engineering haematopoietic stem and progenitor cells (HSPCs)...
Researchers have identified ARL11 as a critical factor in resistance to PARP inhibitor therapy through a genome-wide CRISPR activation screen,...
A Spanish study explores a CRISPR-based gene therapy approach for Ewing sarcoma. The in vivo treatment reduced tumour growth in mice, with no...
Researchers in the UK report a clinically-relevant transplantation strategy using CRISPR-corrected human myogenic cells in hydrogels that generate...
An American study has explored how enlarging the recognition (REC) domain of CRISPR-Cas9 can improve adenine base editing accuracy. The researchers at...
