An American study has explored how enlarging the recognition (REC) domain of CRISPR-Cas9 can improve adenine base editing accuracy. The researchers at...
A new technique developed by Jennifer Doudna and colleagues at the University of California, Berkeley, achieves single-molecule resolution imaging of...
Focused ultrasound (FUS) can significantly improve the efficiency of CRISPR-based genome editing in the brain, according to a new study from the...
Researchers have used a two-guide CRISPR knock-in technique to replace the entire coding sequence (CDS) of the synaptic LRRTM2 protein (Leucine-Rich...
CRISPR interference (CRISPRi) emerges as a promising approach for re-sensitising multidrug-resistant bacteria to antibiotics while avoiding mutations...
Researchers at the University of California San Diego have developed the SCHEMATIC resource, a systematic approach leveraging combinatorial CRISPR...
A new method for directly editing T-cells in lymph nodes using CRISPR-Cas9 aims to enhance immune checkpoint blockade (ICB) cancer therapies. The...
American researchers have used transcriptome-wide CRISPR-Cas13 screens in multiple human cell lines to identify 46 universally essential and more than...