Structural analysis of Cas5 from Moraxella bovoculi reveals that this protein functions equally well as a monomer or a dimer for RNA processing, but...
Japanese researchers have developed a screening system using diphtheria toxin resistance to identify CRISPR-Cas9 variants with enhanced...
Researchers have identified FZD6 as a promising therapeutic target for advanced prostate cancer through systematic screening of Wnt receptors,...
Neurons show slow and distinct DNA repair responses after CRISPR editing, challenging assumptions based on dividing cells. Researchers demonstrate...
Conventional CRISPR-CAS9 tools trigger immune responses in host animals, which can systematically distort screening results and mask genuine cancer...
Two new biotech ventures pursuing heritable genome editing in embryos have raised concern among scientists, reigniting unresolved debates about...
Researchers have used a novel CRISPR-Cas library to identify essential microRNAs in prostate cancer cells, revealing miR-483-3p as a key regulator of...
A genome-wide CRISPR-Cas9 screen to identify transcription factor SOX2 as a critical regulator of PROM1, the gene encoding CD133, in glioblastoma stem...
