Researchers in Peru have developed C12a, a CRISPR-Cas12a-based detection toolbox capable of identifying key antibiotic resistance genes with attomolar...
Spatial Perturb-seq enables pooled in vivo CRISPR screening with single-cell, whole-transcriptome readouts preserved within intact tissue...
Researchers have engineered CIRTS-4G3 – a compact, fully human translational activator built on the CRISPR–Cas-inspired RNA-targeting system (CIRTS)...
A UK and Korean study has developed a machine learning pipeline that integrates single-cell RNA sequencing with CRISPR screens and protein network...
Researchers Profluent Bio have developed Protein2PAM, a deep learning model that predicts and engineers the protospacer-adjacent motif (PAM)...
Genome-wide CRISPR screens in isogenic cell lines have identified synthetic lethal targets across 15 frequently altered cancer drivers, offering new...
Researchers have identified how the bacteriophage protein AcrIIA27 inhibits diverse Cas9 enzymes by binding solvent-exposed regions of the guide RNA...
A new sensitive method detects large-scale chromosomal rearrangements caused by CRISPR-Cas9 genome editing in primary human cells. The approach...
