Researchers at MIT today present DIAL, a modular framework that generates multiple stable expression levels from a single promoter through...
German researchers have employed a sophisticated CRISPR interference screening strategy to systematically investigate how transcription factors...
Chinese researchers have corrected a maple syrup urine disease mutation in patient-derived liver organoids using adenine base editing. The corrected...
Swiss scientists have employed in situ sequencing to track CRISPR-CAS base and prime editing events directly within intact mouse and macaque tissues...
Researchers in Spain have used CRISPR-Cas9 to engineer human cord blood CD34⁺ HSPCs to model the haematologic, immunologic and vascular disorders...
A plasmid-delivered prime editing strategy corrected the glucose-6-phosphate dehydrogenase (G6PD) Viangchan (c.871G>A) mutation in engineered HEK293T...
CRISPR-Cas12b technology was used to edit allogeneic donor islet cells for transplantation into a man with long-standing type 1 diabetes....
Building on prior work demonstrating HIV-1 elimination using dual CRISPR-Cas9 editing and antiretroviral therapy in humanised mice, this study by...
