CRISPR-associated transposons (CASTs) are emerging as powerful tools for genome engineering, offering the ability to insert large DNA fragments...
Researchers in China report that orally-administered CRISPR-Cas9-loaded nanoparticles, designed to target the mitochondrial chaperone TRAP1, overcome...
A new review in Gut explores how advances in RNA-based therapies may impact the treatment of liver metabolic diseases with unprecedented precision and...
Researchers in China report that targeting mutant HTT RNA with CRISPR/CasRx reduces the expression of diseased huntingtin protein and improves...
Scientists engineered ultrasound-controlled CRISPR tools that can precisely edit genes deep within tissues, demonstrating successful gene regulation...
Researchers in Korea report that large DNA deletions occur during DNA repair at a much lower frequency for base editors and prime editors than for...
Researchers in the US report a potentially new therapeutic strategy for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Using...
Researchers in France report the correction of three duplications in the dystrophin gene in cells from Duchenne muscular dystrophy patients, using...
