Researchers in France and Italy have developed a multiplex base editing strategy that simultaneously targets two BCL11A gene enhancers to treat sickle...
Researchers from the Broad Institute and Princeton University have developed two innovative bead-based systems that significantly enhance CRISPR...
Spanish researchers have developed a CRISPR-CAS High Fidelity system that specifically targets G12C and G12D mutations in non-small cell lung cancer....
Building on prior work demonstrating HIV-1 elimination using dual CRISPR-Cas9 editing and antiretroviral therapy in humanised mice, this study by...
A comprehensive CRISPR-CAS whole-genome screen has revealed key proteins controlling anti-sense oligonucleotide (ASO) activity, with a particular...
Scientists have developed a novel gene editing system that significantly enhances targeted gene integration without using viral vectors. The 'enGager'...
Genome-wide association studies have linked the at mass and obesity-associated (FTO) rs9939609-A allele to both obesity and leanness, but the...
A genome-wide CRISPR screen in fibroblasts from patients with Néstor-Guillermo Progeria Syndrome (NGPS) identified 43 genes that mitigate multiple...
