German researchers have employed a sophisticated CRISPR interference screening strategy to systematically investigate how transcription factors...
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A comprehensive CRISPR-CAS whole-genome screen has revealed key proteins controlling anti-sense oligonucleotide (ASO) activity, with a particular...
A high-throughput prime editing screen in human cells reveals that some synonymous mutations, long considered functionally neutral, can significantly...
Researchers have identified a secreted protein that acts as a crucial brake on skin stem cell proliferation, offering new insights into maintaining...
A new CRISPR-based method has been developed to functionally validate hits from pooled knockout screens by measuring shifts in indel profiles that...
Researchers have identified ARL11 as a critical factor in resistance to PARP inhibitor therapy through a genome-wide CRISPR activation screen,...