CRISPR Screens

A CRISPR-based screen has revealed that the transcription factor ZNF740 plays a pivotal role in determining the sensitivity of acute myeloid leukaemia...

Italian researchers have used CRISPR-Cas9 screening to identify long non-coding RNA (lncRNA) RP11-350G8.5 as a key oncogenic factor in multiple...

Three research groups recently independently elucidated the genetic and epigenetic mechanisms driving prostate cancer metastasis. The innovative use...

GlaxoSmithKline Pharma’s Fiona Behan explores synthetic lethality and complex drivers of cancer to identify new therapeutic targets.

Using a genome-wide in vivo CRISPR screen, a team at McGill University Health Centre in Canada identify transforming growth factor beta-3 (TGFβ3) as...