Conventional CRISPR-CAS9 tools trigger immune responses in host animals, which can systematically distort screening results and mask genuine cancer...
Researchers have used a novel CRISPR-Cas library to identify essential microRNAs in prostate cancer cells, revealing miR-483-3p as a key regulator of...
A genome-wide CRISPR-Cas9 screen to identify transcription factor SOX2 as a critical regulator of PROM1, the gene encoding CD133, in glioblastoma stem...
German researchers have employed a sophisticated CRISPR interference screening strategy to systematically investigate how transcription factors...
Some of the best links we picked up around the internet
A comprehensive CRISPR-CAS whole-genome screen has revealed key proteins controlling anti-sense oligonucleotide (ASO) activity, with a particular...
A high-throughput prime editing screen in human cells reveals that some synonymous mutations, long considered functionally neutral, can significantly...
