CRISPR Screens

Researchers at ETH Zürich have introduced a combined base and prime editing approach to explore the mutational landscape of the epithelial growth...

American researchers have used transcriptome-wide CRISPR-Cas13 screens in multiple human cell lines to identify 46 universally essential and more than...

A CRISPR-based screen has revealed that the transcription factor ZNF740 plays a pivotal role in determining the sensitivity of acute myeloid leukaemia...

Italian researchers have used CRISPR-Cas9 screening to identify long non-coding RNA (lncRNA) RP11-350G8.5 as a key oncogenic factor in multiple...

Three research groups recently independently elucidated the genetic and epigenetic mechanisms driving prostate cancer metastasis. The innovative use...

GlaxoSmithKline Pharma’s Fiona Behan explores synthetic lethality and complex drivers of cancer to identify new therapeutic targets.

Using a genome-wide in vivo CRISPR screen, a team at McGill University Health Centre in Canada identify transforming growth factor beta-3 (TGFβ3) as...