A UK and Korean study has developed a machine learning pipeline that integrates single-cell RNA sequencing with CRISPR screens and protein network...
Researchers Profluent Bio have developed Protein2PAM, a deep learning model that predicts and engineers the protospacer-adjacent motif (PAM)...
Genome-wide CRISPR screens in isogenic cell lines have identified synthetic lethal targets across 15 frequently altered cancer drivers, offering new...
Researchers have built a CRISPR-based screening system that directly reads RNA splicing outcomes, using it to uncover medically relevant regulators of...
Some of the best links we picked up around the internet
Structural analysis of Cas5 from Moraxella bovoculi reveals that this protein functions equally well as a monomer or a dimer for RNA processing, but...
Japanese researchers have developed a screening system using diphtheria toxin resistance to identify CRISPR-Cas9 variants with enhanced...
Researchers have identified FZD6 as a promising therapeutic target for advanced prostate cancer through systematic screening of Wnt receptors,...