Researchers have built a CRISPR-based screening system that directly reads RNA splicing outcomes, using it to uncover medically relevant regulators of...
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Structural analysis of Cas5 from Moraxella bovoculi reveals that this protein functions equally well as a monomer or a dimer for RNA processing, but...
Japanese researchers have developed a screening system using diphtheria toxin resistance to identify CRISPR-Cas9 variants with enhanced...
Researchers have identified FZD6 as a promising therapeutic target for advanced prostate cancer through systematic screening of Wnt receptors,...
Conventional CRISPR-CAS9 tools trigger immune responses in host animals, which can systematically distort screening results and mask genuine cancer...
Researchers have used a novel CRISPR-Cas library to identify essential microRNAs in prostate cancer cells, revealing miR-483-3p as a key regulator of...
A genome-wide CRISPR-Cas9 screen to identify transcription factor SOX2 as a critical regulator of PROM1, the gene encoding CD133, in glioblastoma stem...
