Researchers have identified ARL11 as a critical factor in resistance to PARP inhibitor therapy through a genome-wide CRISPR activation screen,...
Scientists have developed a method that allows for simultaneous activation, repression, and knockout of genes within a single cell. By leveraging...
A new method combines multiplexed CRISPR-based gene activation (CRISPRa) with single-cell RNA sequencing (sc-RNA-seq) to identify cis-regulatory...
Researchers have engineered a minimal type I-F2 CRISPR-Cas system capable of transcriptional activation and base editing in human cells. This...
Korean researchers have developed programmable conditional guide RNAs for precise control of endogenous gene expression using the CRISPR-Cas system....
An engineered Cas12a variant offers high-efficiency activation and repression of multiple genes in a single experiment, with applications in cellular...
In 2022, we celebrate a decade of CRISPR as a game-changing tool in research and medicine. The last 10 years have been phenomenal, and CRISPR cures...
Scientists use CRISPR to change the fate of adipocytes, so bad fat is turned into good fat. Effectively treating fat with fat, this might help...
