Delivery

| CRISPR Medicine | This is an overview of articles on delivery

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Highlight: In Utero Nanoparticle Delivery Enables...

Oct. 28, 2024

Delivering mRNA via acid-degradable nanoparticles offers a new frontier in prenatal gene editing, setting the stage for treatments targeting the root...

Engineered Polymers Show Promise for Systemic mRNA...

CMN Interview

Oct. 21, 2024

Scientists engineered nanoparticles capable of delivering genetic material to lung cells with high efficiency when administered intravenously. Based...

Thermostable Cas9 Enhances RNP Performance in Lung...

CMN Briefs

Oct. 17, 2024

Jennifer Doudna and colleagues have engineered a thermostable Cas9 variant, iGeoCas9, which dramatically enhances genome editing efficiency in...

Quantum dots improve CRISPR delivery to microglia

CMN Briefs

Oct. 15, 2024

Researchers in South Korea have developed a cadmium selenide (CdSe) quantum dot (Qdot) system to deliver CRISPR-Cas9 for gene editing in microglia,...

Highlight: CRISPR reduces the cause of blindness...

CMN Briefs

Oct. 7, 2024

In a move to potentially treat blindness, researchers have used CRISPR-Cas9 technology to permanently disrupt VEGFA expression in the eyes of rhesus...

Droplet cell mechanoporation boosts CRISPR...

CMN Briefs

Sep. 16, 2024

Researchers in South Korea have introduced a novel microfluidic platform, termed Droplet Cell Pincher (DCP), to enhance CRISPR-Cas9 genome editing....

Therapeutic Gene Editing. A Lot Done, a Lot More...

CMN Interview

Feb. 5, 2024

For the inaugural episode of CMN Live on 26th January 2024, we spoke with Eric Kmiec, Ph.D. about the successes of therapeutic gene editing to date,...

Gene-Editing Tools: Delivery Methods and...

CMN Special

Jan. 22, 2024

Gene-editing systems, especially CRISPR-Cas9, have revolutionised genome editing, offering potential cures for genetic disorders, cancers, and other...