Researchers at the Gene Editing Institute, ChristianaCare Health System, have used CRISPR to selectively knock down a cancer-specific version of the...
Caribou Biosciences reported last week that its off-the-shelf, CRISPR-edited anti-CD19 CAR-T, vispa-cel (formerly CB-010), achieved response rates and...
Researchers have developed a collection of engineered cytidine deaminases that enable efficient C-to-U RNA base editing across diverse sequence...
CRISPR Therapeutics has presented preclinical data showing that its investigational therapy CTX460 can correct the SERPINA1 Z (E342K) mutation...
Swiss scientists have employed in situ sequencing to track CRISPR-CAS base and prime editing events directly within intact mouse and macaque tissues...
SNIPR Biome has dosed the first patient in its Phase 1b trial of SNIPR001, a CRISPR-CAS-armed bacteriophage therapy that represents a new frontier in...
Researchers in the UK report a clinically-relevant transplantation strategy using CRISPR-corrected human myogenic cells in hydrogels that generate...
A new method for directly editing T-cells in lymph nodes using CRISPR-Cas9 aims to enhance immune checkpoint blockade (ICB) cancer therapies. The...