| CRISPR Medicine | This is our pick of the month best article
A perspective article in Nature Reviews Bioengineering outlines how CRISPR-based RNA silencing could be integrated into ex vivo machine perfusion of...
Alpha-1 antitrypsin deficiency (AATD) has turned into the most crowded proving ground in genetic medicine, with five editing companies reporting fresh...
Scribe Therapeutics is preparing to take its first cardiometabolic programme into the clinic in mid-2026, positioning STX-1150 as a potentially...
Researchers have identified how the bacteriophage protein AcrIIA27 inhibits diverse Cas9 enzymes by binding solvent-exposed regions of the guide RNA...
Researchers in Japan have developed a CRISPR-Cas-based system to edit epigenetic marks in mouse sperm, enabling direct investigation of whether DNA...
A redesigned CRISPR guide RNA system can now switch on multiple human genes in a fixed order, mimicking the staged logic of cell differentiation. The...
Researchers at the Gene Editing Institute, ChristianaCare Health System, have used CRISPR to selectively knock down a cancer-specific version of the...
Conventional CRISPR-CAS9 tools trigger immune responses in host animals, which can systematically distort screening results and mask genuine cancer...