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Jenthera Therapeutics

Company Type: Therapeutics

Main focus: Non-viral delivery of CRISPR-based therapeutics

Company stage: Pre-clinical

Diseases: B-cell lymphoma, small- and non-small cell lung cancer, paediatric B-cell acute lymphoblastic leukaemia

Genome-editing tool: CRISPR-Cas

Funding stage: Seed stage

Location: Saint-Laurent, Canada

Website: https://www.jenthera.com/

Pipeline: https://www.jenthera.com/programs

Partners:

Jenthera Therapeutics is a pre-clinical-stage biotech leveraging its proprietary non-viral delivery technology to develop in vivo CRISPR-based therapeutics. The company's lead internal programme in B-cell lymphoma aims to advance CAR-T therapies, by using its platform’s high frequencies of homology-directed repair to deliver in vivo CAR insertions. The company also has a programme in non-small cell lung cancer. This targets KRAS, a highly prized undruggable oncology target, and represents the first systemically administered ribonucleoprotein CRISPR system achieving targeted delivery to a solid tumour.

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