Danish scientists have developed a web server for gRNA design with a user-friendly graphical interface, which provides interoperability between our on- and off-target prediction tools, CRISPRon and CRISPRoff, for a complete and streamlined gRNA selection. Furthermore, the CRISPRon and CRISPRoff webservers and command-line tools are freely available.
Korean scientists have developed a hybrid CRISPR-Cas protein for one-pot detection of DNA and RNA. The new protein combines Cas12 and Cas13, and the new method successfully detected both WT SARS-CoV-2 and the N501Y mutant variant with a detection limit of 10 viral copies per reaction without cross-reactivity.
"Advances in CRISPR therapeutics" is a review by American researchers. It takes a historical perspective on the application of CRISPR technology to edit the non-coding genome, modulate gene regulation, make precise genetic changes and target infectious diseases that have the potential to lead to curative therapies for many previously untreatable diseases.
News from CRISPR Medicine News
We brought a special update with news from the gene-editing clinical trials on Wednesday. The last few months have seen many updates for gene-editing therapies in development for cancer, HIV, infectious disease and several inherited diseases, and they are all here.
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