Second Part of CRISPRMED25 Opening Day Features Virtual Poster Sessions; Next Four Days Will Be In-Person Sessions

The opening virtual speaker session of Day 1 of the 2^nd Annual CRISPR* Medicine 2025 Conference (CRISPRMED25) was followed by a virtual poster session and a number of the presented posters are highlighted below.

“Precise Gene Writing System for CAR-T Cell Therapy Generation”

One of eleven virtual presentations of the CRISPR Medicine Conference (2025) (Day 1) was given by Paolo Petazzi, PhD, of Integra Therapeutics. In the abstract, the authors noted that “the development of effective, precise, and safe gene-editing technologies for ex vivo therapies, particularly in hematopoietic stem cells (HSCs) and chimeric antigen receptor T cells (CAR-Ts), poses a critical challenge. Current platforms face technical limitations and safety concerns, impeding realization of their full therapeutic potential.” To address these challenges, the authors believe FiCAT (Find and Cut-And-Transfer) emerges as a ground-breaking gene-writing platform with the aim of providing a flexible and universal solution for safe editing of small regions and efficient, programmable editing of large genes in clinically relevant primary cells. “FiCAT is designed to overcome precision and safety limitations in gene editing, streamlining the cell engineering process into a single step. Its potential to reduce costs and eliminate the need for viral vectors promises expanded accessibility to treatment. In summary, FiCAT represents a significant advance in gene editing, poised to enhance precision, safety, and cost-effectiveness in clinical applications.”

Continue reading the virtual poster presentation roundup at BioQuick News here.