Researchers in China report that orally-administered CRISPR-Cas9-loaded nanoparticles, designed to target the mitochondrial chaperone TRAP1, overcome...

A new review outlines genetic engineering strategies, including CRISPR, to enhance the therapeutic potential of innate immune cells in cancer...

A study published today in Nature Communications demonstrates a CRISPR-Cas9 strategy for engineering haematopoietic stem and progenitor cells (HSPCs)...

Researchers have identified ARL11 as a critical factor in resistance to PARP inhibitor therapy through a genome-wide CRISPR activation screen,...

A Spanish study explores a CRISPR-based gene therapy approach for Ewing sarcoma. The in vivo treatment reduced tumour growth in mice, with no...

Researchers at ETH Zürich have introduced a combined base and prime editing approach to explore the mutational landscape of the epithelial growth...

A new method for directly editing T-cells in lymph nodes using CRISPR-Cas9 aims to enhance immune checkpoint blockade (ICB) cancer therapies. The...

American researchers have used transcriptome-wide CRISPR-Cas13 screens in multiple human cell lines to identify 46 universally essential and more than...