Utilizing CRISPR screening, the deubiquitinase ATXN3 has been identified as a key regulator of PD-L1 transcription in tumor cells, a critical factor...

Days before expected FDA approval of its sickle cell gene therapy, Casgevy, CRISPR Therapeutics unveils revisions to its immuno-oncology portfolio and...

Some of the best links we picked up around the internet

Some of the best links we picked up around the internet

There are currently four clinical-stage gene-editing candidates in clinical trials for sickle cell disease, which affects millions of people worldwide...

In this clinical trial roundup, we look at ongoing trials of gene-edited therapies for cancers of the gastrointestinal tract.

In this update, we summarise the two ongoing gene-editing clinical trials for renal cell carcinoma, which is the most common form of kidney cancer...

In recent years, researchers have turned to gene editing to address the limitations of CAR T therapies. This roundup summarises the clinical-stage...