Researchers have developed a compact, all-in-one CRISPR-dCas9-based repressor platform delivered via AAV, effectively silencing gene expression...
Korean researchers have developed programmable conditional guide RNAs for precise control of endogenous gene expression using the CRISPR-Cas system....
In a recent study, researchers in Italy addressed the critical need for experimental validation of durable epigenetic silencing after transient...
Leading epigeneticist Gabriella Ficz has used CRISPR technology to investigate the interplay between DNA methylation and cancer. Her latest findings...
CRISPR-Cas is seen as the holy grail in medicine for rare and incurable genetic diseases. In this piece, we take a look at what CRISPR can do for...
Researchers found a highly efficient repressor for CRISPRi experiments, ZIM3, which can repress gene expression far better than popular alternatives....
Off-target editing is a significant problem with CRISPR and something that scientists really want to protect genomes from. And protection is exactly...
In this roundup, we look back on our interviews with scientists who are making strides in developing CRISPR-based cures for genetic diseases.