Gene-editing systems, especially CRISPR-Cas9, have revolutionised genome editing, offering potential cures for genetic disorders, cancers, and other...

At a length of around 100 nucleotides, single guide RNAs are not synthesised efficiently. However, thanks to click chemistry, they can now be...

A CRISPR-based therapy for the metabolic liver disease phenylketonuria (PKU) has moved one step forward. In vivo prime editing in neonate mice...

To make CRISPR medicines available for patients with genetic diseases, size matters. In a seminal article published today in Molecular Cell,...

Chinese researchers have invented a novel system, AdBlue, to construct adenovirus vectors for CRISPR-Cas9 mediated gene editing. The novel system is...

Almost complete efficiency of gene knock-in is achieved with a new CRISPR-based system developed by researchers from AstraZeneca. The system also...

CRISPR-Cas is seen as the holy grail in medicine for rare and incurable genetic diseases. In this piece, we take a look at what CRISPR can do for...