A new method for directly editing T-cells in lymph nodes using CRISPR-Cas9 aims to enhance immune checkpoint blockade (ICB) cancer therapies. The...

Gene-editing systems, especially CRISPR-Cas9, have revolutionised genome editing, offering potential cures for genetic disorders, cancers, and other...

Leading epigeneticist Gabriella Ficz has used CRISPR technology to investigate the interplay between DNA methylation and cancer. Her latest findings...

In this roundup, we provide a summary of the ongoing gene-editing trials for beta thalassemia. This update includes trials sponsored by Vertex...

Folding DNA into compact structures allows for efficient integration of large genes, and this might lead to new therapies for genetic diseases with...

At a Danish hospital, researchers have integrated CRISPR gene editing into a clinical scale workflow for immunotherapy. Gene editing releases a brake...

Diabetic mice on a high-fat diet gain less weight and have enhanced glucose tolerance after transplantation with CRISPR-edited human cells. The...

A recent study reports the first ever application of base editing to protect immune cells against HIV infection. This is achieved without introducing...