Prime editing combines the powerful DNA-scanning and sequence-identification capabilities of the CRISPR-Cas9 system with a reverse transcriptase...
In this explainer, we introduce base editors, a relatively new class of gene editors that combine the powerful DNA-scanning and...
Gene drives are genetic elements that can quickly spread through populations and have nearly a 100% chance of passing the genes they carry to the next...
Base editors are fusion enzymes that can modify the genome by making precise single base changes without introducing a double-stranded break. This...
CRISPR-associated transposases (CASTs), which probably evolved as an elegant adaptation mechanism in bacteria, represent a novel CRISPR-based...
Prime editing is the newest CRISPR tool that allows broad manipulation of genomic DNA without the requirement for potentially deleterious...
Gene editing targets the root of genetic conditions by editing the DNA, and current clinical trials use one of four targeting strategies. Here we look...
For CRISPR genome editing, it is important to consider what form the agent is delivered. In this explainer, we look at the different forms (plasmid...
