CMN Weekly (20 December 2024) - Your Weekly CRISPR...
CMN Weekly
Dec. 20, 2024
Relevant Interviews, Webinar and Trial Updates posted by CRISPR Medicine News.
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Precision Biosciences
Main focus: Gene editing for the treatment of genetic diseases and cancer
Company stage: Clinical
Diseases: Non-hodgkins lymphoma (NHL), multiple myeloma, B-cell acute lymphoblastic leukaemia (ALL), chronic lymphocytic leukaemia (CLL), small lymphocytic lymphoma (SLL), Duchenne muscular dystrophy, primary hyperoxaluria type 1, chronic hepatitis B infection.
Genome editing tool: megaNuclease
Funding stage: Public (NASDAQ:DTIL)
Location: Durham, North Carolina, US
Website: https://precisionbiosciences.com/
Pipeline: https://precisionbiosciences.com/pipeline/
Partners: Eli Lilly, SpringWorks Therapeutics, iECURE
Precision Biosciences utilises its proprietary ARCUS genome-editing plaform to develop novel CAR-T and gene-editing therapies. The platform is based on the homing endonuclease I-CreI that allows for single, highly specific DNA edits. The company has advanced multiple CAR-T programmes to clinical trials, mainly for the treatment of haematological cancers. Furthermore, the company has a broad in vivo gene correction pipeline under development for the treatment of genetic diseases.
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Clinical Trials
IND Enabling
Phase I
Phase II
Phase III
Participants Who Received an Allogeneic Chimeric Antigen Receptor T-Cell Product (PBCAR) in a Precision BioSciences, Inc., Clinical Study (NCT05822427)
Sponsors:
Precision BioSciences, Inc.
Sponsors:
Precision BioSciences, Inc.
IND Enabling
Phase I
Phase II
Phase III
IND Enabling
Phase I
Phase II
Phase III
IND Enabling
Phase I
Phase II
Phase III
IND Enabling
Phase I
Phase II
Phase III
IND Enabling
Phase I
Phase II
Phase III
